Entropix Welcomes Frazer McKie to its Growing Team of Enzyme Development Specialists
Frazer McKie has recently joined the business as a Research Scientist after completing his industrial research project with Entropix. Frazer has recently completed his MSc in Molecular Biology and Biotechnology (Distinction) and developed codon optimisation software for Entropix’s protein workflow. He brings a wealth of skills and experience in biochemical engineering, cellular systems engineering, programming […]
How do enzymes work? Part 1
A dramatic image of a cytosine-specific DNA methytransferase caught in the act of modifying its target nucleic acid. Taken from the work of Xiaodong Cheng and Rich Roberts and their colleagues The title of this post might seem an elementary question, and one for which a satisfactory answer would appear in an Internet search within […]
Entropix Welcomes Rhys Diggins and Jodie Ashford to the Enzyme Development Team
Rhys Diggins and Jodie Ashford have started their Research Scientist roles at Entropix, bringing a wealth of skills that will advance our enzyme development and optimisation work. Rhys joins us after completing his MSc in Molecular Biology and Biotechnology (Distinction) at The University of Sheffield and achieving a First-Class degree in Biology from Swansea University. […]
Entropix Laboratory Expansion
State-of-the-art laboratory will significantly expand the efficiency and throughput of the Entropix directed enzyme evolution process. We have recently expanded our laboratory space at Sci-Tech Daresbury and invested in new equipment dedicated to improving Entropix’s directed evolution process and protein analysis capabilities. In addition to the expansion, the procurement of robotic liquid handling and automated […]
Entropix Strengthens Board with Appointment of Experienced Non-Executive Director
Industry leader Dr David Pears joins the Entropix board and brings a wealth of expert knowledge in relation to specialty chemicals and technology commercialisation. Entropix has recently appointed Dr David Pears to its board as Non-Executive Director. David has over 30 years’ senior experience in the chemical industry, spanning global multinational manufacturers to high-growth, early-stage […]
Cofactors Lend a Helping Hand
A low resolution physical model of the enzyme L-glutamate dehydrogenase from C. symbiosum. The cofactor NAD is shown bound to the hexameric enzyme in white. The inset shows the bound NAD in the enzyme active site at high resolution. This work is from the laboratories of Professors David Rice and Paul Engel at the University […]
Entropix Meets with Innovate UK and STFC
Entropix CEO Dr Rob Rule recently hosted Indro Mukerjee (CEO of Innovate UK) and delegates from The Science and Technology Facilities Council (STFC) at our Sci-Tech Daresbury laboratory. It was an opportune meeting to discuss the science behind enzyme engineering and bio catalysis and how the directed evolution of enzymes may help to solve some […]
Moonlighting Enzymes
Ten years ago, when I was explaining the molecular basis of enzyme specificity to a group of students, I mentioned that the enzyme, aconitase exhibted two independent functions. It led me to write a short Blog post on what was at the time a relatively new concept in enzymology called “moonlighting”. That is, the unexpected alternative functions or […]
Research Scientist Vacancy – Computational Biology/Machine Learning
Entropix Ltd is a dynamic young biotech business created in 2021 and is based in laboratories at SciTech Daresbury, UK. At Entropix, we aim to improve the sustainability of plastics by developing enzymes that are capable of degrading plastic products that would otherwise become litter or landfill. Our technology for the development of enzymes relies […]
Entropix Collaborates with the Virtual Engineering Centre (VEC)
Proof-of-Concept Study – Machine Learning for Effective Enzyme Identification and Research Entropix Ltd is an early-stage biotechnology company based at Sci-Tech Daresbury in Cheshire, UK. The enzyme development company is developing enzymes with improved performance using synthetic biology and computational analysis techniques. Entropix supports multiple industry sectors including diagnostics, pharmaceuticals, personal care, food, flavours, fragrances, […]