Streamlining DNA Purification Without Compromising Quality: Entropix NADA™ Technology Validated at the University of Sheffield.
Entropix is proud to announce that its innovative NADA™ (Nucleic Acid Depletion and Agent) technology has been successfully validated in a recent study conducted in Professor Simon Foster’s lab at the University of Sheffield. The results confirm that NADA™ delivers rapid, highly effective DNA purification, significantly streamlining workflows for molecular biology and genomics applications.
Dr Mariana Tinajero-Trejo, Research Associate at the University found that NADA™ dramatically reduces processing times while maintaining exceptional DNA quality and yield—making it an ideal solution for high-throughput environments and time-sensitive diagnostics. The study compared the extraction and purification of the NADA™ technology with a leading commercial kit for gram-positive bacteria (MRSA SH1000 ΔsosA). NADA™ was found to be more efficient than the commercial kit, reducing the time for purification after extraction from 1 hour to less than 10 minutes, without reducing quality.
Dr Tinajero-Trejo said “the NADA™ process was so rapid and easy to use compared with the commercial kits, which require repeated sample washing steps. It’s also more sustainable with fewer single-use plastic tubes”
Figure 1 – Comparison between Commercial Kit and NADA-ALGO™ purification for gram-positive genomic DNA isolation from an MRSA (SH1000 ΔsosA)
Prof David Hornby, CSO and co-founder of Entropix said “This work highlights NADA’s potential to transform laboratory efficiency and reliability, offering a powerful tool for academic, clinical, and industrial labs alike. As the demand for fast, accurate genetic analysis continues to grow, Entropix’s NADA™ technology stands at the forefront of next-generation DNA purification.”
Trials are currently ongoing alongside several commercial partners to test the streamlining effect of NADA™ on a diversity of nucleic acid purification workflows and applications. Those who wish to express their interest in testing NADA™ should contact Dr Rob Rule, CEO at Entropix Ltd: [email protected].